Main bioactive phenolic compounds in marine algae and their mechanisms of action supporting potential health benefits

Food Chem. 2021 Mar 30;341(Pt 2):128262. doi: 10.1016/j.foodchem.2020.128262. Epub 2020 Oct 1.

Abstract

Given the growing tendency of consumers to choose products with natural ingredients, food industries have directed scientific research in this direction. In this regard, algae are an attractive option for the research, since they can synthesize a group of secondary metabolites, called phenolic compounds, associated with really promising properties and bioactivities. The objective of this work was to classify the major phenolic compounds, compare the effectiveness of the different extractive techniques used for their extraction, from traditional systems (like heat assisted extraction) to the most advance ones (such as ultrasound, microwave or supercritical fluid extraction); the available methods for identification and quantification; the stability of the enriched extract in phenolic compounds and the main bioactivities described for these secondary metabolites, to offer an overview of the situation to consider if it is possible and/or convenient an orientation of phenolic compounds from algae towards an industrial application.

Keywords: Algae; Bioactivities; Catechin (PubChem CID9064); Catechin gallate (PubChem CID6419835); Eckol (PubChem CID145937); Eckstolonol (PubChem CID10429214); Epigallocatechin (PubChem CID72277); Extraction techniques; Ferulic acid (PubChem CID445858); Gallic acid (PubChem CID370); Industrial applications; Phenolic compounds; Phloroglucinol (PubChem CID359); Sinapic acid (PubChem CID637775); Triphloroethol A (PubChem CID21626545).

MeSH terms

  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / isolation & purification
  • Anti-Infective Agents / pharmacology*
  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Phenols / chemistry
  • Phenols / isolation & purification
  • Phenols / pharmacology*
  • Plant Extracts / chemistry*
  • Seawater
  • Seaweed / chemistry*
  • Structure-Activity Relationship

Substances

  • Anti-Infective Agents
  • Antineoplastic Agents, Phytogenic
  • Antioxidants
  • Phenols
  • Plant Extracts