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Foodomics technology: promising analytical methods of functional activities of plant polyphenols

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Abstract

Polyphenol compounds are widely found in natural plants and they are attracting a lot of interests in their functional activities including anti-cancer, anti-inflammatory, liver-protection, anti-bacteria, neuroprotection, anti-obesity, and other related effects. However, the mechanisms of polyphenolic functional activities are still limited. Although chemical reagent methods have been widely used to study various polyphenol activities, it is difficult to deeply investigate the specific mechanism of polyphenol activities in vivo only by chemical methods. Recently, as a method to discover biomarkers associated with polyphenol activities, foodomics technique including proteomics, metabolomics, genomics, transcriptomics and lipidomics technique was developed to study the mechanisms. In this review, we summarized the worldwide research advances of polyphenolic functional activities using foodomics techniques.

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Acknowledgements

This study was supported by the National Science Foundation of China (Grant No. 31701604), Scientific Research Foundation of Wuhan Institute of Technology (Grant No. k201633), the Key Program of Hubei Provincial Department of Education (Grant No. D20171501), Graduate Innovative Fund of Wuhan Institute of Technology (Grant No. CX2020354).

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Authors and Affiliations

  1. School of Environmental Ecology and Biological Engineering, Wuhan Institute of Technology, Wuhan, 430205, China

    Fang Yang, Chenyang Xie, Jie Li, Renyi Ma & Zhixiong Dang

  2. School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan, 430205, China

    Cunwen Wang & Tielin Wang

  3. Key Laboratory for Green Chemical Process of Ministry of Education, Wuhan Institute of Technology, Wuhan, 430205, China

    Fang Yang, Cunwen Wang & Tielin Wang

  4. Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, Wuhan Institute of Technology, Wuhan, 430205, China

    Fang Yang, Cunwen Wang & Tielin Wang

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  1. Fang Yang
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Correspondence to Cunwen Wang or Tielin Wang.

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Yang, F., Xie, C., Li, J. et al. Foodomics technology: promising analytical methods of functional activities of plant polyphenols. Eur Food Res Technol 247, 2129–2142 (2021). https://doi.org/10.1007/s00217-021-03781-3

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