Abstract
Hibiscus sabdariffa L. (HS) calyx extracts have been well-documented for the treatment of hypertension, liver dysfunctions, and diabetes among others. An updated concise review of HS regarding phytoconstituents, and involved putative mechanisms of potential biological activities is presented. HS showed other food and other industrial applications, including the preparation of metallic nanoparticles. These activities were explained by the presence of a broad spectrum of valuable phytochemicals, including the red pigments anthocyanins, phenolic, and organic acids and polyphenolics (e.g., flavonoids and tannins). Most of the bioactivities were found to be associated with anthocyanins-rich extracts. Anthocyanins were found to have various mechanisms for the treatment of hypertension, including direct vasodilation and inhibition of angiotensin-converting enzyme (ACE). However, leaves and seeds showed also other potential applications in food industry, owing to the significant amounts of phenolic antioxidant compounds. Therefore, valorization and optimization of bioactive constituents’ extraction from plant biowastes should be considered for maximizing the benefits of HS extracts.
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References
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MAS and AZ designed the manuscript’s topics. MEB, MMA, RFBK and FAG wrote the manuscript. SME revised the revised final version. All the authors have approved the final submitted version.
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Mohamed A. Salem has no conflict of interest. Ahmed Zayed has no conflict of interest. Magy E. Beshay has no conflict of interest. Mirna M. Abdel Mesih has no conflict of interest. Reem F. Ben Khayal has no conflict of interest. Fady A. George has no conflict of interest. Shahira M. Ezzat has no conflict of interest.
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Salem, M.A., Zayed, A., Beshay, M.E. et al. Hibiscus sabdariffa L.: phytoconstituents, nutritive, and pharmacological applications. ADV TRADIT MED (ADTM) 22, 497–507 (2022). https://doi.org/10.1007/s13596-020-00542-7
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DOI: https://doi.org/10.1007/s13596-020-00542-7